• Reduce text

    Reduce text
  • Restore text size

    Restore text size
  • Increase the text

    Increase the text
  • Print

    Print
Bioinformatics / statistics / microbial
Reference
1538124165
Deadline for applications
11/01/2018
Date of publication
09/28/2018

Details

Details on the type of contract
Temporary assignment
Duration of contract
15 months
Beginning
01/01/2019

Remuneration
2339€ / month
Professional field
Informatics, statistics and scientific calculations

Assignment

Name of unit of assignment
UMR1213 UMRH Unité Mixte de Recherche sur les Herbivores
Address of unit of assignment
INRA Site de Theix 63122 SAINT-GENES-CHAMPANELLE
Website of unit of assignment
http://www1.clermont.inra.fr/urh/
Region of assignment
Auvergne Rhône-Alpes

Description

Working environment

UMR1213 Herbivores is a joint research unit associating Inra and VetAgro Sup. It contributes to the design of sustainable farming systems for herbivores that seek to reconcile production efficiency, product quality and socio-economic viability with environmental protection and valuation, and animal welfare. UMR1213 Herbivores assesses both on-farm practices and predominant and alternative systems of herbivore farming, and proposes innovative techniques with high environmental value. To achieve this aim, UMR1213 Herbivores analyses and integrates the underlying biological mechanisms, and establishes laws for animal responses with approaches ranging from high-throughput techniques to modelling and decision support tools for various stakeholders (producers, consumers, citizens, and policy-makers).

Context :

The METHLAB project was funded under the 1st FACCE ERA-GAS Joint Call. This proposal is focused on implementing the use of lactic acid bacteria (LAB) as an approach to reduce methane emissions from ruminant livestock. The goal will be to refine current on-farm LAB technologies such as direct-fed microbial supplements and/or silage inoculants, currently used to increase production and improve health of animals, with a methane-reducing benefit. INRA will screen lactic acid bacteria strains for their antimethanogenic potential on in vitro rumen assays of mixed rumen microbes. Results will be shared with partners in order to select the most promising strains in terms of methane reduction potential. Transcriptomic and metabolomic approaches will be applied to elucidate the molecular mechanisms of probiotic functionalities of the selected lactic acid bacteria (top 5 to 10). Metatranscriptomics is relevant for identifying genes or genetic pathways that are up or down regulated in response to the inclusion of probiotics to the assay of mixed rumen microbes. The candidate will:

  • define analysis strategies for the amplicon and RNASeq data
  • perform bioinformatic analysis
  • implement statistical test
Training and skills required

 

We are looking for a highly motivated individual with:

  • Master / Engineering degree in bioinformatics / biostatistics
  • Experience in Galaxy administration
  • RNAseq desired experience
  • Experience in the use of a computing server
  • Advanced use of R software
  • Ability to interact with biologists

Send a motivation letter and a CV to Milka Popova

Contact

Name
Milka Popova
Telephone
+33473624727
Email
milka.popova@inra.fr